Journal: Brain Sciences
Article Title: Rewarding and Reinforcing Effects of 25H-NBOMe in Rodents
doi: 10.3390/brainsci12111490
Figure Lengend Snippet: Effect of 25H-NBOMe administration on the place conditioning paradigm in mice. Time difference spent in the drug-paired (white bar) and drug-unpaired (black bar) compartment between the drug administration group and the vehicle (saline) group during pre-conditioning and post-conditioning (0: circles, 25H-NBOMe 0.05 mg/kg: squares, 25H-NBOMe 0.1 mg/kg: triangles, 25H-NBOMe 0.5 mg/kg: down triangles, METH 1 mg/kg: diamonds). Data are expressed as mean ± SEM ( n = 8 each group). * p < 0.05; ** p < 0.01 vs. vehicle, determined by a two-way ANOVA followed by Bonferroni’s post-hoc test.
Article Snippet: The place conditioning apparatus (MED-CPP-3013AT, Med Associates, Inc., St. Albans, VT, USA) consisted of three compartments, including black, white, and gray (central) compartments, separated by guillotine doors.
Techniques: Saline